3D Imaging
Imaging Whole Biological Samples in 3D including Bone and Dense Tissue and Agricultural Samples in High Resolution
Introduction to 3D Imaging
3D imaging enables the capture of entire sample volumes, providing precise X, Y, and Z measurements for a deeper spatial understanding of data. This perspective allows for more accurate analysis of complex structures, such as the cardiovascular system or whole embryos, revealing details that would be lost in 2D imaging.
High-Resolution Episcopic Microscopy (HREM) and Its Impact on 3D Imaging
HREM is a 3D block-face imaging technique designed for high-contrast visualisation of whole structures. By integrating a specialised microtome with advanced optics, it generates detailed 2D images that collectively form a complete volumetric dataset.
Optical HREM systems support various block-face imaging and fluorescence techniques, making them ideal for high-density samples. With sub-micron XY resolution and a Z resolution of 1 micron, HREM delivers powerful 3D data for precise analysis.
3D Imaging Examples and Applications
3D imaging enables high-resolution visualisation and analysis of diverse biological and agricultural samples, providing detailed structural and morphological insights. Key applications include:
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Cardiovascular Research – High-resolution imaging of mouse hearts and vascular systems for studying congenital heart defects and developmental anomalies.
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Embryo Morphology & Gene Expression – Whole-embryo imaging to analyse structural development, gene expression patterns, and phenotypic variations.
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Agricultural & Plant Science – 3D imaging of crops and biological specimens, including barley, citrus fruit, and chicken embryos, for developmental studies and genetic research.
Tools for 3D Image Visualisation and Processing
Explore our self made tools designed to streamline 3D imaging workflows. From visualising 2D image stacks in 3D to advanced image stitching and processing, these solutions enhance data analysis without complex setups or long loading times (and are free to use :))
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3D Viewer – A powerful yet intuitive tool for visualising 2D image stacks in 3D, offering seamless depth exploration with no complex setup—completely free to use.
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2D Image Viewer – Load and explore entire 2D datasets instantly with an optimised TIFF stack viewer, designed for fast and efficient visualisation.
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Image Pipeline Creator – Build custom processing pipelines to refine 3D image stacks for external viewing, with options to adjust physical resolution for enhanced analysis.
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3D Image Stitching – Align and blend 2D images into precise 3D volumes with central Z-axis alignment, featuring both manual and automated stitching for seamless integration.
Contact our team
Contact our team to for a quote or more information on 3D imaging.
Phone:
+44(0) 1462633500
Email:
hello@indigo-scientific.co.uk
More Info
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For more information or a quote use contact us
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Browse the dedicated HREM page